Related Experiment Video
Updated: Aug 6, 2025

Manual Restraint and Common Compound Administration Routes in Mice and Rats
Published on: September 26, 2012
[Needle spiking, injecting people with a substance without their knowledge or consent]
Hille Koppen1,2, Femke M J Gresnigt3, Paula van Ruyven1
1HagaZiekenhuis, afd. Neurologie, Den Haag.
Background:
In the Netherlands therewereseveralreports on needlespiking: people have found themselvessubjectedtosurreptitiousinjections.
Case Description:
A 23-year-old female was seenafterbeingsurroundedby a group of men andfeltwhatshethought was a jab. She was abletoevadethegroup. Several minutes later sheexperienceddizziness, nausea andvomiting. On physical examination, a bleedingpuncturewound was seen on her upper arm withaccompanying erythema. Toxicology on bloodand urine didnot show evidenceforintoxicationotherthan alcohol which was higherthanwouldbesuspectedbythenumber of drinks thevictimreported.
Conclusion:
There is evidencethatpeople are puncturedwithneedles in busy surroundings like thenightlife. Possiblealso drugs are injected. Experiencedsymptomsbyvictims (n=19) wereheterogeneousandnotlikelyattributedtooneandthesamecausal drug. Toxicologydidnotrevealanysubstanceuntilnow.
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