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The Isabel Differential Diagnosis Generator for Orbital Diagnosis
Edsel B Ing1,2, Michael Balas2, Georges Nassrallah1
1Department of Ophthalmology and Vision Science, University of Toronto Temerty Faculty of Medicine, Toronto, Canada.
Ophthalmic Plastic and Reconstructive Surgery
|March 17, 2023
Summary
The Isabel diagnosis tool has limited utility for orbital conditions. It failed to accurately identify many common orbital diseases and tumors in a recent evaluation.
Area of Science:
- Ophthalmology
- Medical Informatics
Background:
- Electronic diagnosis decision support tools aim to aid clinicians.
- The Isabel system is a widely recognized tool in this category.
Purpose of the Study:
- To prospectively evaluate the utility of the Isabel diagnosis system for orbital disease differential diagnosis.
Main Methods:
- Specific orbital terms were input into Isabel.
- Clinical details from 25 orbital surgery textbook cases were entered.
- Isabel's top 10 differential diagnoses were compared to the correct diagnoses.
Main Results:
- Isabel correctly identified only 16% of orbital cases within its top 10 differential diagnoses.
- Common causes of proptosis and orbital tumors were often not elucidated.
- 32% of generated diagnoses were unlikely to cause orbital disease.
Conclusions:
- The Isabel system currently offers limited value for orbital differential diagnosis.
- Incorporating anatomical localization and imaging findings could improve accuracy.
