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Infertility in Females

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Ovaries

Ovaries

The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
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Infertility in Males

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...

Hormonal Control of the Ovarian Cycle

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Vaccinations

Vaccinations

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Updated: Aug 6, 2025

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Published on: October 25, 2024

CoronaVac vaccine does not affect ovarian reserve.

Ayşe Rabia Şenkaya¹, Zafer Çil², Ömür Keskin³

¹Gynecology and Obstetrics Clinic, İzmir Bakırçay University Çiğli Training and Research Hospital, Turkey. dr.aysekanbak@gmail.com.

Ginekologia Polska

|March 17, 2023

Summary

The CoronaVac vaccine showed no significant impact on ovarian reserve markers like Anti-Müllerian Hormone (AMH) or follicle count in infertile women. This suggests vaccination is a safe approach to protect fertility during the COVID-19 pandemic.

Keywords:

CoronaVac anti mullerian hormone infertility ovarian follicle vaccination

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Area of Science:

Reproductive Endocrinology
Vaccinology
Infectious Diseases

Background:

COVID-19 infection is linked to negative effects on female fertility and potential ovarian damage.
Understanding the impact of vaccines on reproductive health is crucial for women of reproductive age.
Previous research indicates a need to assess vaccine safety concerning ovarian reserve.

Purpose of the Study:

To investigate the effect of the CoronaVac vaccine on ovarian reserve in infertile female patients.
To compare key fertility markers before and after COVID-19 vaccination.
To provide evidence regarding the safety of CoronaVac for female reproductive health.

Main Methods:

Retrospective study design involving 46 infertile female patients.
Patients received two doses of CoronaVac vaccine one month apart.
Comparison of Anti-Müllerian Hormone (AMH) levels and folliculometry data before vaccination and one month post-vaccination.

Main Results:

No statistically significant difference was observed in AMH levels before and after CoronaVac vaccination (p = 0.366).
Follicle count also showed no significant change following vaccination (p = 0.610).
The findings indicate that CoronaVac does not negatively affect ovarian reserve markers.

Conclusions:

CoronaVac vaccination appears to be a safe and rational strategy to protect ovarian reserve in women.
The study supports the use of COVID-19 vaccination in women of reproductive age, particularly those facing infertility.
Confirming vaccine safety can encourage wider vaccine uptake among women concerned about fertility.