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Calcium urolithiasis in two dogs with parathyroid adenomas
J S Klausner1, T P O'Leary, C A Osborne
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul 55108.
Journal of the American Veterinary Medical Association
|December 1, 1987
Summary
Primary hyperparathyroidism in dogs can cause calcium urolith formation. Surgical removal of parathyroid adenomas may resolve hypercalcemia and prevent recurrence of calcium stones.
Area of Science:
- Veterinary Medicine
- Endocrinology
- Nephrology
Background:
- Primary hyperparathyroidism (PHPT) is a condition characterized by excessive parathyroid hormone production.
- PHPT leads to hypercalcemia, which can manifest in various clinical signs, including urolithiasis.
- The link between PHPT and calcium-containing uroliths in dogs warrants further investigation.
Observation:
- Two dogs with primary hyperparathyroidism presented with calcium urolith formation.
- One dog had calcium phosphate uroliths surgically removed following parathyroid adenoma excision.
- The second dog had calcium oxalate uroliths that remained stable post-adenoma removal.
Findings:
- Surgical intervention for parathyroid adenoma successfully resolved hypercalcemia and urolithiasis in one dog.
- In the second dog, urolithiasis persisted but remained stable after treatment for PHPT.
- These cases highlight the association between PHPT and canine calcium urolithiasis.
Implications:
- Primary hyperparathyroidism should be considered in the differential diagnosis for dogs presenting with calcium uroliths.
- Diagnostic workup for calcium urolithiasis in dogs should include assessment for hypercalcemia and parathyroid gland abnormalities.
- Successful treatment of PHPT may prevent or manage calcium urolithiasis in affected dogs.