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Related Experiment Videos

Naproxen-induced toxicosis in a dog.

M A Gilmour1, R Walshaw

  • 1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824-1316.

Journal of the American Veterinary Medical Association
|December 1, 1987
PubMed
Summary

Naproxen, a nonsteroidal anti-inflammatory drug, caused severe gastric issues in a dog. Supportive care and a blood transfusion were crucial for the dog's recovery from ulceration and bleeding.

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Area of Science:

  • Veterinary Medicine
  • Pharmacology

Background:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain and inflammation.
  • Naproxen is a widely available NSAID.

Observation:

  • A dog presented with vomiting, anemia, melena, and weakness.
  • These clinical signs were associated with gastric ulceration and bleeding.

Findings:

  • Naproxen administration was identified as the cause of the gastric ulceration and bleeding.
  • The dog's condition improved with supportive treatment, including a blood transfusion, fluid therapy, and gastroprotectants.

Implications:

  • This case highlights the potential gastrointestinal risks of NSAIDs like naproxen in dogs.
  • Veterinary professionals and pet owners should be aware of these adverse effects and consider safer alternatives for pain management in canine patients.

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