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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
Published on: July 11, 2025
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Overcoming the challenges to implementation of artificial intelligence in pathology.
Jorge S Reis-Filho1, Jakob Nikolas Kather2,3,4
1Experimental Pathology, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Journal of the National Cancer Institute
|March 17, 2023
Summary
Artificial intelligence (AI) in pathology can improve diagnostic accuracy and biomarker extraction but faces slow adoption. Overcoming key hurdles is crucial for AI-supported precision oncology.
Area of Science:
- Digital pathology
- Computational pathology
- Artificial intelligence in medicine
Background:
- Pathologists face increasing workloads, impacting patient care quality.
- Artificial intelligence (AI) offers potential to enhance diagnostic accuracy and biomarker discovery from digital slides.
- The adoption of AI in pathology lags behind other medical fields like radiology.
Purpose of the Study:
- To critically review advancements in digital and computational pathology over the past decade.
- To identify and address key challenges hindering AI integration in pathology.
- To offer a future perspective on AI-enabled precision oncology.
Main Methods:
- Review of developments in digital and computational pathology over the last 10 years.
- Analysis of hurdles impacting AI adoption in pathology.
- Formulation of strategies to overcome identified challenges.
Main Results:
- Significant progress in AI applications for pathology, including improved diagnostics and biomarker extraction.
- Persistent challenges in AI implementation, such as workflow integration and regulatory hurdles.
- Identification of pathways to accelerate AI adoption for enhanced patient care.
Conclusions:
- AI holds substantial promise for democratizing expert pathology and advancing precision oncology.
- Addressing current barriers is essential for realizing the full potential of AI in pathology.
- Future integration of AI is expected to revolutionize oncological diagnostics and treatment strategies.

