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Updated: Jul 1, 2026

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
Published on: September 16, 2012
Consensus recommendations on peripheral blood smear review: defining curricular standards and fellow competency
Matthew L Chase1, Reed Drews2, Marc S Zumberg3
1Division of Hematology and Hematologic Malignancies and Division of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA.
Hematology trainees need standardized training for peripheral blood smear (PBS) review, a core clinical skill. This study developed consensus recommendations for PBS education and competency assessment, addressing a critical gap in graduate medical education.
Area of Science:
- Medical Education
- Hematology
- Diagnostic Cytology
Background:
- Graduate medical education in hematology requires competency in peripheral blood smear (PBS) review.
- Current training lacks standardized guidelines for PBS interpretation, education, and competency assessment.
- This deficiency impacts diagnostic accuracy and patient care.
Purpose of the Study:
- To develop consensus recommendations for peripheral blood smear (PBS) review education and competency assessment in hematology.
- To address the absence of standardized guidelines in graduate medical education.
- To inform future curriculum development and research in visuospatial diagnostic tasks.
Main Methods:
- A multi-institutional focus group of eight academic hematologists was convened.
- Constructivist grounded theory and a modified nominal group technique were employed.
- Mixed-methods analysis of focus group data identified emerging theory and generated consensus recommendations (CR).
Main Results:
- Strong consensus was achieved on multiple aspects of PBS education, emphasizing a systematic approach.
- Discussions focused on red and white blood cell disorders, particularly acute leukemia and thrombotic microangiopathies.
- Key recommendations address the need for prompt recognition of critical diagnoses.
Conclusions:
- Consensus recommendations for PBS education and competency were successfully generated.
- These recommendations provide a foundation for future research and curriculum development in hematology training.
- Standardized PBS review training is crucial for ensuring diagnostic proficiency and patient safety.
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