Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.4K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.4K
Coulomb's Law and The Principle of Superposition01:15

Coulomb's Law and The Principle of Superposition

9.1K
Coulomb's Law describes the force experienced by two point charges under each other's presence. But what if there are more than two charges? For example, if there is a third charge, does it experience a force that is a simple combination of the individual forces due to the first two charges? Can it be described mathematically?
The Principle of Superposition answers the question. Yes, Coulomb's Law applies to each pair of charges, and the net force on each charge is the vector sum of...
9.1K
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

671
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
671
Coulomb's Law01:30

Coulomb's Law

9.4K
Experiments with electric charges have shown that if two objects each have an electric charge, they exert an electric force on each other. The magnitude of the force is linearly proportional to the net charge on each object and inversely proportional to the square of the distance between them. The direction of the force vector is along the imaginary line joining the two objects and is dictated by the signs of the charges involved.
Newton's third law applies to the Coulomb force — the...
9.4K
Interpreting ¹H NMR Signal Splitting: The (n + 1) Rule01:10

Interpreting ¹H NMR Signal Splitting: The (n + 1) Rule

1.4K
In the AX proton spin system, proton A can sense the two spin states of a coupled proton X, resulting in a doublet NMR signal with two peaks of equal (1:1) intensity. When proton A is coupled to two equivalent protons (AX2 spin system), the spin states of each X can be aligned with or against the external field, creating three possible scenarios. This results in a 1:2:1  triplet signal, where the central peak corresponds to the chemical shift of A and is twice as large or intense as the...
1.4K
¹H NMR: Complex Splitting01:13

¹H NMR: Complex Splitting

1.3K
A proton M that is coupled to a proton X results in doublet signals for M. However, NMR-active nuclei can be simultaneously coupled to more than one nonequivalent nucleus. When M is coupled to a second proton A, such as in styrene oxide, each peak in the doublet is split into another doublet.
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fast array-based particle coincidence detection in a Timepix3-based velocity map imaging instrument.

The Review of scientific instruments·2026
Same author

PVN mechanisms in OSA comorbidities: from intermittent hypoxia-stress to therapy.

Frontiers in neurology·2026
Same author

Generation of 3.3-mJ, 2.45-µm, sub-2-cycle laser pulses via hollow-core fiber pulse compression.

Optics letters·2026
Same author

Spatial Mapping of Valence Excited-State Landscapes Using Time-Resolved Shake-Down Spectroscopy.

The journal of physical chemistry. A·2026
Same author

Evolution of Robotic-Assisted Sympathetic Trunk Reconstruction: Technical Innovation and Clinical Experience.

Seminars in plastic surgery·2026
Same author

Chronic Neuralgia After Single-Port Versus Multiport Trans-Subxiphoid Robotic Mediastinal Surgery: A Prospective Single-Arm Pilot Study With Historical Controls.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026
Same journal

Erratum: Bacterial Turbulence at Compressible Fluid Interfaces [Phys. Rev. Lett. 136, 138301 (2026)].

Physical review letters·2026
Same journal

Unveiling Light-Quark Yukawa Flavor Structure via Dihadron Fragmentation at Lepton Colliders.

Physical review letters·2026
Same journal

Adaptable Route to Fast Coherent State Transport via Bang-Bang-Bang Protocols.

Physical review letters·2026
Same journal

Topological Transition and Emergence of Elasticity of Dislocation in Skyrmion Lattice: Beyond Kittel's Magnetic-Polar Analogy.

Physical review letters·2026
Same journal

Pound-Drever-Hall Method for Superconducting-Qubit Readout.

Physical review letters·2026
Same journal

Coupling a ^{73}Ge Nuclear Spin to an Electrostatically Defined Quantum Dot in Silicon.

Physical review letters·2026
See all related articles

Related Experiment Video

Updated: Aug 6, 2025

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.4K

Multiparticle Cumulant Mapping for Coulomb Explosion Imaging.

Chuan Cheng1, Leszek J Frasinski2, Gönenç Moğol1

  • 1Department of Physics and Astronomy, Stony Brook University, Stony Brook, New York 11794, USA.

Physical Review Letters
|March 17, 2023
PubMed
Summary
This summary is machine-generated.

We developed a new four-particle imaging technique, cumulant mapping, enabling high-count-rate measurements for studying ultrafast molecular dynamics. This method overcomes limitations of traditional covariance analysis by correcting for spurious correlations.

More Related Videos

Direct Imaging of Laser-driven Ultrafast Molecular Rotation
10:52

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

9.8K
Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−
06:53

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−

Published on: July 27, 2018

8.8K

Related Experiment Videos

Last Updated: Aug 6, 2025

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

10.4K
Direct Imaging of Laser-driven Ultrafast Molecular Rotation
10:52

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

9.8K
Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−
06:53

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−

Published on: July 27, 2018

8.8K

Area of Science:

  • Atomic, Molecular, and Optical Physics
  • Chemical Physics
  • Ultrafast Science

Background:

  • Covariance velocity map imaging is a powerful technique for studying molecular dynamics.
  • Traditional methods struggle with high event rates and require coincidence detection.
  • Understanding ultrafast structural changes in molecules is crucial for advanced research.

Purpose of the Study:

  • To extend covariance velocity map imaging to four particles.
  • To establish cumulant mapping for high-count-rate measurements.
  • To investigate ultrafast molecular dynamics in formaldehyde using few-cycle laser pulses.

Main Methods:

  • Developed a fourfold covariance analysis extended to cumulant mapping.
  • Implemented a full cumulant calculation to subtract pairwise correlations.
  • Applied the technique to the four-body breakup of formaldehyde via strong-field ionization.

Main Results:

  • Demonstrated cumulant mapping for four-particle coincidence-free measurements at high rates.
  • Successfully applied the method to formaldehyde breakup using 30 fs and 6 fs laser pulses.
  • Highlighted distinct ultrafast dynamics observable with different pulse durations.

Conclusions:

  • Cumulant mapping significantly enhances Coulomb explosion imaging capabilities.
  • The technique provides insights into ultrafast structural dynamics previously inaccessible.
  • This advancement is particularly valuable for high-count-rate experiments, such as with XFELs.