Source toxicity characteristics of short- and medium-chain chlorinated paraffin in multi-environmental media: Product...

Short and medium-chain chlorinated paraffin (SCCP/MCCP) have been widely studied because of their extensive environmental hazards. In this study, product source toxicity, molecular source toxicity and food chain migration of SCCP and MCCP in multi-environmental media were comprehensively considered. The additive combination of SCCP and MCCP in the air, water and soil environment was adjusted, and PVC, PU and rubber products with the lowest source toxicity were screened. The source toxicity of SCCP and MCCP in the water environment was inhibited by design of the feed additive addition scheme (highest inhibition was 16.29 %), and the source toxicity of SCCP and MCCP in the soil environment was affected by different field management measures (highest inhibition was 38.22 %). A forage fertilizer addition plan, a cattle feed addition plan and a special population healthy complementary food regulation plan were developed to prevent the migration step by step and absorption of SCCP and MCCP in the terrestrial food chain. In addition, by means of density functional theory and analysis of key amino acid residues, the mechanism of toxicity difference between SCCP and MCCP was analyzed from the level of chemical interaction, and rationality of the inhibition scheme designed in this study was verified.