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Lung Transplant After a Heart Transplant: A Case Report
Jee Young You1, Sarah Park2, Jason Turowski1
1Department of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
Transplantation Proceedings
|March 17, 2023
Summary
A staged heart transplant followed by a lung transplant is possible. This approach may reduce transplant wait times and suggests early interstitial lung disease isn't a contraindication for heart transplants.
Area of Science:
- Cardiology
- Pulmonology
- Transplant Surgery
Background:
- End-stage heart and lung disease often necessitates combined heart-lung transplantation.
- Sequential heart and lung transplantation is rarely reported.
- Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease.
Observation:
- A patient with idiopathic pulmonary fibrosis underwent a heart transplant.
- Six years post-heart transplant, the patient developed end-stage lung disease requiring a left single lung transplant.
- This staged approach was successfully performed.
Findings:
- The left single lung transplant was successful 6 years after the initial heart transplant.
- The patient's outcome demonstrates the feasibility of a staged heart-lung transplant strategy.
- Early-stage interstitial lung disease did not preclude successful heart transplantation.
Implications:
- This case suggests a staged heart-lung transplant approach can be a viable option.
- It may help mitigate prolonged waiting times for lung allografts.
- Early interstitial lung disease may not be an absolute contraindication for initial heart transplantation.
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