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Monkeypox epidemiology, clinical presentation, and transmission: a systematic review
Ashima Sharma1, Hari Prasad2, Nidhi Kaeley3
1Department of Emergency Medicine, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, 500082, India.
International Journal of Emergency Medicine
|March 18, 2023
Summary
Monkeypox transmission is increasing globally. This review analyzes 2352 cases, highlighting key demographic and clinical trends to inform targeted prevention and treatment strategies for this zoonotic viral infection.
Area of Science:
- Epidemiology and Public Health
- Infectious Diseases
- Viral Zoonoses
Background:
- Monkeypox is an emerging zoonotic viral infection posing a significant global health challenge.
- Understanding its epidemiology, clinical presentation, and transmission is crucial for effective public health response.
Purpose of the Study:
- To investigate the epidemiology, clinical characteristics, complications, and case fatality rate of monkeypox.
- To analyze transmission patterns in recent monkeypox cases.
Main Methods:
- A systematic literature search was conducted in PubMed, Google Scholar, and Science Direct.
- Studies published in English, focusing on data from 2022 onwards, were included; reviews and commentaries were excluded.
Main Results:
- Analysis of 26 articles covering 2352 confirmed monkeypox cases.
- Approximately 81.71% of cases involved men who have sex with men (MSM), and 30.18% were HIV positive.
- Male sex was identified as a risk factor, with human-to-human and human-to-animal transmission rates rising.
Conclusions:
- Rising transmission rates necessitate further research into monkeypox prevention, clinicodemographic trends, and treatment.
- A targeted and focused approach is essential for managing monkeypox patients effectively.
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