Bézier interpolation improves the inference of dynamical models from data
Kai Shimagaki1, John P Barton1,2
1Department of Physics and Astronomy, University of California, Riverside, California 92521, USA.
Abstract:
Many dynamical systems, from quantum many-body systems to evolving populations to financial markets, are described by stochastic processes. Parameters characterizing such processes can often be inferred using information integrated over stochastic paths. However, estimating time-integrated quantities from real data with limited time resolution is challenging. Here, we propose a framework for accurately estimating time-integrated quantities using Bézier interpolation. We applied our approach to two dynamical inference problems: Determining fitness parameters for evolving populations and inferring forces driving Ornstein-Uhlenbeck processes. We found that Bézier interpolation reduces the estimation bias for both dynamical inference problems. This improvement was especially noticeable for data sets with limited time resolution. Our method could be broadly applied to improve accuracy for other dynamical inference problems using finitely sampled data.
Related Concept Videos
Reconstruction of Signal using Interpolation
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
BIBO stability of continuous and discrete -time systems
To determine the BIBO stability, the convolution integral is utilized when a bounded continuous-time input is applied to a Linear Time-Invariant (LTI) system....
Prediction Intervals
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y.
Modeling and Similitude
Model Approaches for Pharmacokinetic Data: Physiological Models


