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Past and current thyroid function in subjects with panic disorder.

I M Lesser1, R T Rubin, R B Lydiard

  • 1Department of Psychiatry, Harbor/UCLA Medical Center, Torrance 90509.

The Journal of Clinical Psychiatry
|December 1, 1987
PubMed
Summary
This summary is machine-generated.

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Thyroid dysfunction is not a common cause of panic disorder symptoms. While patients reported more thyroid illness history, current thyroid dysfunction was rare and unrelated to panic or phobia severity.

Area of Science:

  • Endocrinology
  • Psychiatry
  • Medical Research

Background:

  • Thyroid function disturbances can mimic anxiety disorder symptoms, particularly panic disorder.
  • Previous research suggests a link between thyroid illness and panic/phobic disorders, but direct investigation is limited.

Purpose of the Study:

  • To assess the relationship between thyroid function and panic disorder.
  • To investigate if thyroid dysfunction contributes to panic and phobic symptoms.

Main Methods:

  • Measured thyroid function indices in 165 subjects with DSM-III diagnoses of panic disorder.
  • Compared prevalence of self-reported thyroid illness history with general population data.
  • Assessed correlation between thyroid function and severity of panic attacks/phobias.

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Main Results:

  • Subjects reported a higher prevalence of thyroid illness by history than the general population.
  • Less than 1% of subjects exhibited current thyroid dysfunction.
  • No correlation found between thyroid function indices and panic attack or phobia severity.
  • Major depressive episodes were unrelated to current thyroid function but associated with higher thyroid disease history.

Conclusions:

  • Current thyroid dysfunction is uncommon in patients diagnosed with panic disorder.
  • Thyroid function does not appear to be a significant factor in the severity of panic or phobic symptoms.
  • Further research may explore the historical reporting of thyroid illness in this population.