Periprosthetic joint infection caused by kytococcus schroeteri: The first reported case and a review of the literature
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Published on: February 2, 2024
Alberto A Zellner1, Gunnar T Hischebeth2, Ernst Molitor3
1Department of Orthopedics and Trauma Surgery, University Clinic of Bonn, Bonn, Germany.
Abstract:
Oftentimes, Gram-positive cocci are the cause for periprosthetic joint infections (PJI). Most of these infections include bacteria such as Staphylococcus aureus, Staphylococcus epidermidis or other coagulase-negative staphylococci. We here present the first case of a PJI caused by Kytococcus schroeteri. While being a Gram-positive coccus, it is very rarely the cause for infections in the human body. K. schroeteri is part of the micrococcus branch and often encountered as a symbiotic bacterium living on the skin. Regarding its pathogenic potential, not a lot is known since less than a few dozen human infections have been reported worldwide. Furthermore, many of the cases reported are either associated with implanted material, especially heart valves, or associated with patients whose immune response is deficient. Only 3 reports of osteoarticular infections are described so far.
Insights
This study reports the first case of Kytococcus schroeteri causing a periprosthetic joint infection (PJI). This rare Gram-positive coccus, typically skin-dwelling, highlights a new pathogen in orthopedic implant infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Orthopedics
Background:
- Periprosthetic joint infections (PJI) are frequently caused by Gram-positive cocci.
- Common culprits include Staphylococcus aureus and coagulase-negative staphylococci.
- Kytococcus schroeteri is a rarely implicated Gram-positive coccus, typically found as skin commensal.
Observation:
- This report details the first documented case of Kytococcus schroeteri causing a PJI.
- K. schroeteri is part of the micrococcus branch, with limited known pathogenic potential.
- Few human infections by K. schroeteri have been documented, often linked to implants or immunocompromised patients.
Findings:
- Kytococcus schroeteri was identified as the causative agent of a periprosthetic joint infection.
- This represents a novel pathogen in the context of orthopedic implant-related infections.
- Only three prior reports of osteoarticular infections by this bacterium exist.
Implications:
- This case expands the spectrum of known pathogens capable of causing PJI.
- It underscores the need for broader microbiological consideration in recalcitrant joint infections.
- Further research into K. schroeteri's pathogenicity and clinical significance is warranted.
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