One-quarter of COVID-19 patients developed PTSD symptoms: A one-year longitudinal study

Luna Sun1, Zhilei Shang1, Lili Wu1

  • 1Lab for Post-traumatic Stress Disorder, Faculty of Psychology and Mental Health, Naval Medical University, Shanghai, China; The Emotion & Cognition Lab, Faculty of Psychology and Mental Health, Naval Medical University, Shanghai, China.

Psychiatry Research
|March 19, 2023
PubMed

Insights

COVID-19 survivors experienced a significant decrease in probable post-traumatic stress disorder (PTSD) symptoms one year after hospital discharge. However, female patients and those with respiratory issues faced a higher risk of chronic PTSD, necessitating psychological support.

Area of Science:

  • Medical Research
  • Psychiatry
  • Pulmonology

Background:

  • COVID-19 survivors often experience long-term physical and psychological effects.
  • Post-traumatic stress disorder (PTSD) is a recognized sequela of severe illness and hospitalization.

Purpose of the Study:

  • To investigate the longitudinal development of PTSD symptoms in COVID-19 survivors one year post-discharge.
  • To identify risk factors for chronic PTSD among COVID-19 survivors.
  • To examine the relationship between respiratory sequelae and PTSD development.

Main Methods:

  • A cohort of 329 COVID-19 survivors was followed for 12 months after hospital discharge.
  • PTSD symptoms were assessed at 3 and 12 months post-discharge.
  • Statistical analyses were performed to determine symptom changes and risk factors.

Main Results:

  • The cumulative incidence of probable PTSD decreased from 23.1% at 3 months to 4.3% at 12 months.
  • Non-severe COVID-19 patients showed improvement in all PTSD symptom clusters, while severe patients improved in re-experiencing and numbing symptoms.
  • Female sex and the presence of respiratory sequelae were identified as risk factors for chronic PTSD.

Conclusions:

  • While most COVID-19 survivors show improvement in PTSD symptoms over time, a subset remains at risk.
  • Respiratory sequelae and female sex are significant predictors of persistent PTSD.
  • Long-term psychological interventions are crucial for managing PTSD in COVID-19 convalescence.

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