Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Aug 6, 2025

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

12.5K

Engineering natural based nanocomposite inks via interface interaction for extrusion 3D printing.

João Rocha Maia1, Edgar Castanheira1, João M M Rodrigues1

  • 1Department of Chemistry, CICECO - Aveiro Institute of Materials, Aveiro, Portugal.

Methods (San Diego, Calif.)
|March 19, 2023
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A blood-brain barrier model based on flexible tubes to tailor the biophysical and chemical environment for drug delivery testing.

Materials today. Bio·2026
Same author

Nature's blueprint: Exopolysaccharides linking microbiome dynamics to advanced bone tissue engineering.

Carbohydrate polymers·2026
Same author

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Unraveling the potential and challenges of photosynthetic microalgae for oxygenating engineered tissues.

Biomaterials advances·2026
Same author

Superbase ionic liquid mediated solubilization of curcumin for improved bioavailability and anticancer efficacy.

Scientific reports·2026
Same author

Thermoresponsive Complex Coacervates as Advanced Carriers for Cell-Laden Liquid-Core Capsules for Biomedical Applications.

Small (Weinheim an der Bergstrasse, Germany)·2026

Chemical crosslinking enhances bioactive glass nanoparticle (BGNP) and protein nanocomposites for 3D printing. This versatile method creates tunable, light-responsive inks with improved rheology and homogeneous filler distribution.

Area of Science:

  • Biomaterials Engineering
  • Additive Manufacturing
  • Nanotechnology

Background:

  • Nanocomposites and low-viscosity materials face challenges in additive manufacturing due to poor rheology and preparation issues.
  • Chemical crosslinking offers a universal solution to improve material properties for 3D printing.

Purpose of the Study:

  • To develop a chemical crosslinking strategy for creating tunable, light-responsive nanocomposite inks.
  • To improve the rheological properties and homogeneity of bioactive glass nanoparticle (BGNP) and methacrylated bovine serum albumin (BSAMA) systems for 3D printing.

Main Methods:

  • Utilized amine-functionalized BGNP and light-responsive BSAMA as the model system.
  • Employed 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide and N-Hydroxysuccinimide for interfacial crosslinking between BGNP and BSAMA.
Keywords:
3D printingBioactive glass nanoparticlesBiomaterial inkDouble-crosslinkedNanocompositeProtein-based biomaterialsSurface functionalization

More Related Videos

Hybrid Printing for the Fabrication of Smart Sensors
08:35

Hybrid Printing for the Fabrication of Smart Sensors

Published on: January 31, 2019

8.2K
Planar and Three-Dimensional Printing of Conductive Inks
10:49

Planar and Three-Dimensional Printing of Conductive Inks

Published on: December 9, 2011

37.3K

Related Experiment Videos

Last Updated: Aug 6, 2025

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

12.5K
Hybrid Printing for the Fabrication of Smart Sensors
08:35

Hybrid Printing for the Fabrication of Smart Sensors

Published on: January 31, 2019

8.2K
Planar and Three-Dimensional Printing of Conductive Inks
10:49

Planar and Three-Dimensional Printing of Conductive Inks

Published on: December 9, 2011

37.3K
  • Investigated varying amounts of crosslinking agent and BGNP concentrations.

    • Main Results:

    • Crosslinking significantly improved elastic and viscous modulus across all formulations.
    • Optimal results were achieved with 4% w/v crosslinking agent and 10% w/w BGNP, yielding the highest Young's modulus.
    • Formulations demonstrated effective BGNP immobilization and suitability as 3D printing inks.

    Conclusions:

    • A versatile chemical crosslinking methodology was established for producing tunable, light-responsive nanocomposite inks.
    • The approach ensures homogeneous distribution of bioactive fillers and broadens applicability for various material phases.
    • This method addresses key limitations in translating nanocomposites for additive manufacturing.