Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

2.4K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
2.4K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.7K
Asthma I: Introduction01:28

Asthma I: Introduction

112
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
112
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

49
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
49

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Case of Abscess of the Left Lung; Thickening and Partial Ulceration of the Pericardium; Adhesion of the Right Lung, and Extensive Tubercular Deposition through the Entire Pulmonary Structure; with Obscure Diagnosis.

Medical examiner (Philadelphia, Pa.)·2023
Same author

Time trade-off study to establish utility decrements in individuals with a spinal cord injury who perform intermittent catheterization.

Journal of medical economics·2023
Same author

Treatment outcomes of patients with Atopic Dermatitis (AD) treated with dupilumab through the Early Access to Medicines Scheme (EAMS) in the UK.

The Ulster medical journal·2021
Same author

Dos and don'ts of writing for Br J Oral Maxillofac Surg.

The British journal of oral & maxillofacial surgery·2020
Same author

Psychological intervention (ConquerFear) for treating fear of cancer recurrence: mediators and moderators of treatment efficacy.

Journal of cancer survivorship : research and practice·2019
Same author

Mitchell-Hoole-Kanatas (MHK) questionnaire: the first to measure patient-reported outcomes relating to problems with intimacy after diagnosis and treatment of head and neck cancer.

The British journal of oral & maxillofacial surgery·2018

Related Experiment Video

Updated: May 3, 2026

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

40.2K

Clinical and immunologic studies among egg-processing workers with occupational asthma.

D I Bernstein1, A B Smith, D R Moller

  • 1Department of Medicine, University of Cincinnati Medical Center, OH 45267.

The Journal of Allergy and Clinical Immunology
|December 1, 1987
PubMed
Summary

Egg processing workers exposed to inhaled egg proteins can develop occupational asthma. Immunologic tests, including skin prick tests and specific IgE (RAST), identified sensitization linked to asthma symptoms.

More Related Videos

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

9.1K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.9K

Related Experiment Videos

Last Updated: May 3, 2026

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

40.2K
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

9.1K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.9K

Area of Science:

  • Occupational Health
  • Immunology
  • Allergology

Background:

  • Egg processing factories involve exposure to airborne egg proteins.
  • Respiratory sensitization to food allergens can lead to occupational diseases.

Purpose of the Study:

  • To evaluate respiratory sensitization to inhaled egg proteins in egg-processing factory workers.
  • To identify specific egg allergens responsible for occupational asthma.

Main Methods:

  • Physician evaluation, serial peak expiratory flow rate (PEFR) measurements, skin prick tests, serum-specific IgE (RAST), and specific IgG (ELISA) were used.
  • Allergens included whole egg, egg white/yolk powders, and purified egg white fractions (ovalbumin, ovomucoid, lysozyme, conalbumin).

Main Results:

  • Five of 25 workers diagnosed with definite asthma, four with occupational asthma.
  • Asthma significantly associated with cutaneous reactivity and RAST binding to egg allergens (p<0.01).
  • Elevated specific IgG responses to whole egg, lysozyme, and conalbumin found in exposed workers compared to controls.

Conclusions:

  • Inhaled egg proteins can cause occupational asthma in egg-processing workers.
  • Specific IgE (RAST) and skin reactivity to egg allergens are key indicators of sensitization and asthma.
  • Further research into specific egg protein fractions like ovomucoid and ovalbumin is warranted.