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Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

29
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
29
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

1.7K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.7K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

19
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
19
Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

411
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
411
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

479
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
479
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

30
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
30

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Related Experiment Video

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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

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Heart failure and depression: A perspective from bibliometric analysis.

Mei Ieng Lam1,2, Pan Chen1,3, Xiao-Meng Xie4

  • 1Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Taipa, Macao SAR, China.

Frontiers in Psychiatry
|March 20, 2023
PubMed
Summary

Research on heart failure and depression shows rapid growth, primarily led by North America and Europe. Future studies should focus on self-care and anxiety in heart failure patients.

Keywords:
bibliometricscardiac failuredepressionheart failurehotspots

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Area of Science:

  • Cardiology
  • Psychiatry
  • Bibliometrics

Background:

  • Depression is a common comorbidity in heart failure (HF) patients.
  • Depression negatively impacts HF patients' quality of life and prognosis.
  • Bibliometric analysis provides insights into HF and depression research trends.

Purpose of the Study:

  • To explore the research landscape of heart failure and depression using bibliometric methods.
  • To identify key trends, influential countries, authors, and keywords in this field.
  • To highlight emerging research areas and future directions.

Main Methods:

  • A comprehensive literature search was conducted on June 24, 2022.
  • Bibliometric analysis was performed using the Bibliometrix package in R.
  • VOSviewer and CiteSpace software were used for visualization and citation burst analysis.

Main Results:

  • A total of 8,221 publications were identified between 1983 and 2022.
  • The United States led in publications and citations, followed by China, Germany, Italy, and Japan.
  • Key terms included "heart failure," "depression," "quality of life," "mortality," and "myocardial infarction," with recent focus on "self-care" and "anxiety."

Conclusions:

  • Research on heart failure and depression has grown rapidly, predominantly from North America and Europe.
  • Future research should investigate self-care and anxiety in heart failure.
  • Further analysis of non-English publications is recommended.