Related Experiment Video
Updated: Aug 6, 2025

Cut-loading: A Useful Tool for Examining the Extent of Gap Junction Tracer Coupling Between Retinal Neurons
Published on: January 12, 2012
YES to Junctions, No to Src
Michael Simons1, Derek Toomre1
1Yale Cardiovascular Research Center and Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06511.
Abstract:
Regulation of the endothelial barrier function is critical to physiological function of the vasculature, which must dynamically change in a number of physiologic and pathologic settings. A new study emphasizes the complex relationship between VE-cadherin phosphorylation , the critical role of YES in this process, and the vascular leak.
Related Concept Videos
Anchoring Junctions
RC Circuit without Source
Applying Kirchhoff's current law at the top node of the circuit and substituting the current values across the components, a first-order differential equation is obtained. By rearranging the terms...
RL Circuit without Source
Applying Kirchhoff's voltage law around the loop of the circuit and substituting the voltages across the inductor and resistor yields a first-order differential equation. A logarithmic equation is obtained by rearranging the terms in this equation,...
RC Circuit with Source
Due to the inherent properties of a capacitor, its voltage cannot change instantaneously. This means that immediately after the switch is closed, the capacitor's voltage remains the same as it was just before the switch was closed.
Source Transformation
It is essential to note that when...
Underflow Gates

