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Updated: Aug 6, 2025

A Murine Tail Lymphedema Model
Published on: February 10, 2021
Chylothorax and chylous ascites: Overview, management, and nutrition
Nicholas T Duletzke1, Laszlo N Kiraly1, Robert G Martindale1
1Department of Surgery, Oregon Health and Science University, Oregon, Portland, USA.
Abstract:
Chyle leaks of any source or type can cause significant morbidity and mortality. Attention to the anatomy and physiology of the leak, followed by stepwise dietary and pharmacologic management, obviates the need for surgical intervention in a majority of patients. In this article, we review the importance, etiology, anatomy, diagnosis, nutrition and immunologic effects, and options for treatment of chylothorax and chylous ascites based on experience and prior literature. We propose a multidisciplinary approach to optimize these treatments including the primary surgical teams, pharmacists, and dietitians, with reoperation as a last resort to minimize the morbidity of this challenging complication.
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