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Evolving Management of Acute Mastoiditis: Analysis of the Pediatric Health Information System Database
Tzyynong L Friesen1,2, Matt Hall3, Nanda Ramchandar4
1Department of Otolaryngology, University of California San Diego, San Diego, California, USA.
Insights
Surgical management for acute mastoiditis decreased over time in US pediatric centers. Despite declining surgery rates, patient outcomes remained excellent, with younger, complicated cases more likely to receive surgical treatment.
Area of Science:
- Otolaryngology
- Pediatric Medicine
- Health Services Research
Background:
- Optimal management for acute mastoiditis lacks consensus.
- Existing research primarily consists of small, single-institution retrospective studies.
- There is a need for broader analysis of treatment trends and outcomes.
Purpose of the Study:
- To analyze the treatment of acute mastoiditis in US pediatric centers.
- To examine changes in management strategies over time.
- To compare outcomes between surgical and nonsurgical approaches.
Main Methods:
- Retrospective analysis of an administrative database (Pediatric Health Information System).
- Inclusion of patients aged ≤18 years diagnosed with acute mastoiditis from 2010-2019.
- Statistical analysis using Cochran-Armitage Trend Test, chi-squared, and Wilcoxon rank sum tests.
Main Results:
- A total of 2170 patients were analyzed, with 57.5% undergoing surgery.
- Significant decreases observed in myringotomy (64% to 47%) and mastoidectomy (22% to 10%) rates from 2010 to 2019.
- Surgically treated patients were younger, more likely to have complications, and had longer hospital stays and higher ICU utilization, yet similar readmission and mortality rates.
Conclusions:
- Acute mastoiditis treatment has evolved, with a notable decline in surgical interventions.
- Surgical management is more common in younger patients with complications.
- Overall outcomes for acute mastoiditis remain favorable regardless of surgical approach.
Objective:
The optimal management of acute mastoiditis remains controversial. Most existing studies are retrospective single-institutional experiences with small cohorts. Our objectives were to analyze the treatment of acute mastoiditis by pediatric centers across the United States and changes in management over time.
Study Design:
Retrospective analysis.
Setting:
Administrative database study using Pediatric Health Information System.
Methods:
Patients ≤18 years of age who were admitted with a principal diagnosis of acute mastoiditis from January 1, 2010 to December 31, 2019 were included. Trends were assessed by Cochran-Armitage Trend Test. χ2 and Wilcoxon rank sum tests were used to compare outcomes between the surgical and nonsurgical groups.
Results:
A total of 2170 patients met the inclusion criteria, with 1248 (57.5%) requiring surgical management. The rate of surgical procedures decreased significantly over time. The rate of myringotomy decreased from 64% in 2010 to 47% in 2019 (p < .001), and mastoidectomy decreased from 22% in 2010 to 10% in 2019 (p < .001). On admission, 29% of the cohort presented with mastoiditis-related complications. Patients treated surgically were younger (p < .001), more likely to present with complications (37.5% vs 17.5%, p < .001), required longer length of stay (3.7 vs 2.3 days, p < .001), and had higher intensive care unit utilization (8.6% vs 2.2%, p < .001). However, the rate of 30-day readmission, emergency department return, and in-hospital mortality were all similar.
Conclusion:
Acute mastoiditis has been successfully treated with declining rates of a surgery over time. Younger patients who present with complications are more likely to be managed surgically, and the overall outcomes remain excellent.
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