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Relationship Between Alcohol Intolerance and Aspirin-Exacerbated Respiratory Disease (AERD): Systematic Review
Estephania Candelo1, Monet McCalla2, Oriana A Valderrama3
1Department of Otolaryngology and Head-Neck Surgery, Mayo Clinic Jacksonville, Jacksonville, Florida, USA.
Patients with aspirin-exacerbated respiratory disease (AERD) frequently experience alcohol intolerance. Medical therapies, such as aspirin desensitization, may improve alcohol tolerance in individuals with AERD.
Area of Science:
- Immunology
- Otolaryngology
- Pulmonology
Background:
- Aspirin-exacerbated respiratory disease (AERD) is a clinical triad of asthma, nasal polyposis, and bronchospasm following aspirin ingestion.
- Previous research indicates a potential link between AERD and alcohol intolerance.
Conclusions:
- The current evidence suggests a significant risk of alcohol intolerance in patients diagnosed with AERD.
- Aspirin desensitization presents a potential therapeutic strategy to enhance alcohol tolerance in this population.
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