Related Experiment Video
Updated: Aug 6, 2025

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
Published on: February 8, 2020
Monovision Correction Preference and Eye Dominance Measurements
Victor Rodriguez-Lopez1, Xoana Barcala1,2, Amal Zaytouny1
1Institute of Optics, Spanish National Research Council (IO-CSIC), Madrid, Spain.
Purpose:
To propose new methods for eye selection in presbyopic monovision corrections.
Methods:
Twenty subjects with presbyopia performed two standard methods of binary eye dominance identification (sensory with +1.50 diopters [D ]and +0.50 D and sighting with "hole-in-the-card") and two psychophysical methods of perceived visual quality: (1) the Preferential test, 26 natural images were judged with the near addition in one eye or in the other in a 2-interval forced-choice task, and the Eye Dominance Strength (EDS) defined as the proportion of trials where one monovision is preferred over the other; (2) the Multifocal Acceptance Score (MAS-2EV) test, the perceived quality of a natural images set (for 2 luminance levels and distances) was scored and EDS defined as the score difference between monovision in one eye or the other. Left-eye and right-eye dominance are indicated with negative and positive values, respectively. Tests were performed using a Simultaneous Vision Simulator, which allows rapid changes between corrections.
Results:
Standard sensory and sighting dominances matched in only 55% of subjects. The Preferential EDS (ranging from -0.7 to +0.9) and MAS-2EV EDS (ranging from -0.6 to +0.4) were highly correlated. Selecting the eye for far in monovision with the MAS-2EV, sensory, or sighting tests would have resulted in 79%, 64%, and 43% success considering the Preferential test as the gold standard.
Conclusions:
Tests based on perceptual preference allow selection of the preferred monovision correction and measurement of dominance strength.
Translational Relevance:
The binocular visual simulator allows efficient implementation of eye preference tests for monovision in clinical use.

