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Weight of babies conceived in vitro
M P Diamond1, G Lavy, J B Russell
1Department of Obstetrics and Gynecology, Yale-New Haven Hospital, Connecticut 06510.
Journal of in Vitro Fertilization and Embryo Transfer : IVF
|October 1, 1987
Summary
Infants conceived via in vitro fertilization (IVF) are not inherently predisposed to low birth weight or early delivery. Previous findings may be influenced by factors like patient anxiety leading to earlier births.
Area of Science:
- Reproductive Medicine
- Neonatal Health
- Obstetrics
Background:
- Previous studies indicated a potential link between in vitro fertilization and embryo transfer (IVF-ET) and lower infant birth weights.
- This raised concerns about the developmental outcomes for infants conceived through assisted reproductive technologies.
Purpose of the Study:
- To investigate the relationship between birth weight and estimated gestational age (EGA) in infants born after IVF-ET.
- To determine if IVF-ET itself is a risk factor for low birth weight or preterm delivery.
Main Methods:
- A retrospective review of infants delivered between May 1, 1983, and July 15, 1986, at the institution.
- Analysis of delivery mode, gestational age, birth weight, and size for gestational age (using the Lubchenco scale).
Main Results:
- Out of 39 deliveries (45 infants), 42 were term births (after 36 weeks).
- The mean birth weight for term infants was 3225 +/- 90 g.
- Most infants (38/45) were appropriate for gestational age; seven were macrosomic (above the 90th percentile).
Conclusions:
- Infants conceived via IVF-ET do not appear to be predisposed to low birth weight or early gestational age.
- Observed lower birth weights in prior studies might be attributed to early deliveries prompted by patient anxiety or pressure.