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Updated: Aug 6, 2025
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Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
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Randomized controlled trial comparing open anterograde anatomic radical retropubic prostatectomy with retrograde
Fabricio B Carrerette1, Daniela B Rodeiro1, Rui T F Filho1
1Department of Surgery (Urology), Pedro Ernesto University Hospital of State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Asian Journal of Urology
|March 21, 2023
Summary
The anterograde technique for radical prostatectomy offers improved outcomes for localized prostate cancer patients, showing reduced bleeding and better urinary continence compared to the retrograde method.
Area of Science:
- Urology
- Surgical Oncology
Background:
- Radical prostatectomy is standard for localized prostate cancer but carries risks.
- Robot-assisted surgery aims to reduce morbidity and speed recovery.
- This study developed an open prostatectomy protocol to match robotic outcomes without new instruments.
Purpose of the Study:
- To compare the efficacy of anterograde versus retrograde techniques in open radical prostatectomy.
- To evaluate postoperative outcomes including bleeding, continence, and complications.
Main Methods:
- 220 patients with localized prostate cancer underwent radical prostatectomy.
- Patients were divided into anterograde (115) and retrograde (105) technique groups.
- Outcomes assessed at 3 months post-surgery.
Main Results:
- The anterograde technique showed significantly reduced bleeding (p=0.0003) and faster anastomosis (p=0.005).
- Urinary continence at 3 months was higher with the anterograde technique (60.9%) vs. retrograde (42.9%) (p=0.007).
- Fewer and less severe complications were observed with the anterograde method (p=0.007 and p=0.0006).
Conclusions:
- The anterograde technique is more efficient in reducing complications after radical prostatectomy.
- This open approach offers advantages over the retrograde method for localized prostate cancer treatment.
