Related Experiment Video
Updated: Aug 6, 2025

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Candy cane syndrome presenting with refractory heartburn 15 years after Roux-en-Y bypass
Shahana Prakash1,2, Ramses Saavedra3, Ryan Lehmann3
1Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Candy cane syndrome (CCS), a rare Roux-en-Y gastric bypass complication, can present with heartburn years later. Early diagnosis and surgical correction of the long afferent limb are crucial for symptom resolution.
Area of Science:
- Gastroenterology
- Bariatric Surgery
Background:
- Roux-en-Y gastric bypass (RYGB) is a common bariatric procedure.
- Candy cane syndrome (CCS) is a rare complication characterized by an excessively long afferent jejunal limb.
- Typical CCS symptoms include abdominal pain, nausea, and vomiting.
Observation:
- A 57-year-old female presented with 7 months of refractory heartburn post-RYGB.
- Upper endoscopy identified a 9 cm blind afferent jejunal limb, indicative of CCS.
- This case represents the longest reported duration (15 years) from RYGB to CCS symptom onset.
Findings:
- Heartburn is an uncommon presenting symptom for CCS.
- Surgical resection of the elongated afferent limb successfully resolved the patient's symptoms.
Implications:
- Clinicians should consider CCS in RYGB patients with refractory heartburn, irrespective of the time since surgery.
- Maintaining a high index of suspicion for CCS is vital for timely diagnosis and effective management.
- This case expands the known clinical presentation and timeline of CCS.
Related Concept Videos
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Endoscopic Procedures V: ERCP
Patient...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...

