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[Challenges to global pertussis prevention and control]
Insights
Pertussis, a dangerous respiratory illness, is seeing a resurgence despite high vaccination rates. This review examines the global epidemic status, reemergence factors, and control challenges for pertussis.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Pertussis, caused by Bordetella pertussis, is a major global cause of infant morbidity and mortality.
- High vaccination coverage has been maintained globally since 1974 through the expanded program on immunization.
- Recent years have seen increased pertussis incidence and outbreaks in numerous countries, challenging previous control efforts.
Conclusions:
- The reemergence of pertussis poses a significant public health threat, necessitating updated control strategies.
- Understanding the complex factors driving pertussis resurgence is crucial for effective prevention.
- Addressing the challenges in pertussis prevention and control requires a multi-faceted approach.
Abstract:
Pertussis is an acute, highly infectious respiratory disease caused by Bordetella pertussis, and is one of the leading causes of infant disease and death worldwide. The pertussis vaccine has been used in the expanded program on immunization globally since 1974 and the vaccination coverage remains high. In recent years, the pertussis incidence rate increased, even pertussis outbreaks occurred, in more and more countries or areas after years with low incidence level. The disease burden of pertussis has been seriously underestimated, and the prevention and control of pertussis is facing many challenges. This article reviews the epidemic status of pertussis worldwide, the factors affecting the reemergence of pertussis, and the challenges in the prevention and control to provide a reference for prevention and control of pertussis.
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