Endometrial receptivity evaluation using hysteroscopic endometrial gland image recognition

Area of Science:

• Reproductive Medicine
• Infertility Research
• Medical Imaging

Background:

• Endometrial receptivity is crucial for successful in vitro fertilization and embryo transfer (IVF-ET).
• Assessing endometrial receptivity and predicting pregnancy outcomes remain challenging.
• Endometrial gland density is a potential indicator of uterine receptivity.

Purpose of the Study:

• To evaluate endometrial receptivity by counting endometrial glands on hysteroscopic images.
• To determine if endometrial gland count can predict pregnancy outcomes in patients undergoing frozen-thawed embryo transfer (FET).

Main Methods:

• Hysteroscopic endometrial imaging was performed 3-7 days post-ovulation in 98 patients undergoing FET in a natural cycle.
• An automated algorithm was used to count endometrial glands from hysteroscopic images.
• Patients were categorized into pregnancy and non-pregnancy groups to compare gland counts.

Main Results:

• No significant differences were observed in patient demographics or laboratory parameters between groups.
• The pregnancy group exhibited a significantly higher number of endometrial glands compared to the non-pregnancy group (p < 0.05).

Conclusions:

• Hysteroscopic endometrial gland counting is a viable method to assess endometrial receptivity.
• Increased endometrial gland count may be associated with improved pregnancy rates in IVF-ET.
• This technique offers a potential tool for optimizing fertility treatments.