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[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Fluoroalkyl Sulfoximines for Versatile Photocatalytic Radical Fluoroalkylations
1Department of Applied Chemistry, Faculty of Fundamental Engineering Nippon Institute of Technology E24-315, 4-1 Gakuendai, Miyashiro-Machi, Minamisaitama-gun, Saitama, 345-8501, Japan.
Abstract:
Fluoroalkyl sulfoximines, which serve as electron-accepting fluoroalkyl radical sources, are easy-to-handle, solid, and bench-stable chemicals. Fluoroalkyl radicals can be generated from sulfoximine reagents using strong one-electron injectors, such as a highly reducing photoredox catalyst in the excited state. Our group has developed photocatalytic radical di- and mono-fluoromethylation and α-monofluoroalkylation of olefins with the corresponding fluoroalkyl sulfoximines. In this personal account, appropriate combinations of fluoroalkyl sulfoximines and photoredox catalysts, leading to successful radical fluoroalkylation, have been discussed.
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