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Induction of Ocular Surface Inflammation and Collection of Involved Tissues
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Inflammatory eye disease for rheumatologists.

Kelly Corbitt1, Johannes Nowatzky1,2,3

  • 1New York University Grossman School of Medicine, Department of Medicine, Division of Rheumatology.

Current Opinion in Rheumatology
|March 21, 2023
PubMed
Summary
This summary is machine-generated.

This review offers a framework for rheumatologists to diagnose and manage inflammatory eye diseases like uveitis and scleritis. It emphasizes multidisciplinary care to preserve vision in patients with these complex ocular conditions.

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Area of Science:

  • Ophthalmology and Rheumatology
  • Ocular inflammation and systemic disease
  • Multidisciplinary patient care

Background:

  • Inflammatory eye diseases present diagnostic and management challenges for rheumatologists.
  • Conditions discussed include uveitis, scleritis, episcleritis, peripheral ulcerative keratitis, and orbital inflammation.
  • Heterogeneity and rarity of these diseases complicate research and treatment standardization.

Approach:

  • Provides a framework for diagnosis, differential diagnosis, and management strategies.
  • Discusses current therapeutic mainstays: glucocorticoids, mycophenolate, methotrexate, and TNF inhibitors.
  • Highlights the need for a collaborative approach between rheumatologists and ocular inflammation specialists.

Key Points:

  • Multidisciplinary care is essential for optimal outcomes in inflammatory eye disease.
  • Understanding disease specifics (phenotypes and endotypes) is crucial for research and clinical practice.
  • Early and accurate diagnosis and treatment are vital for vision preservation.

Conclusions:

  • This review aims to enhance rheumatologists' ability to co-manage patients with ocular inflammation.
  • Facilitates the development of improved approaches to inflammatory eye diseases.
  • Emphasizes the importance of specialized care for preserving vision in affected patients.