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Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

23
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
23
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

23
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
23
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

320
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
320
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

19
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
19
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

30
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
30
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

21
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
21

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Related Experiment Video

Updated: Aug 6, 2025

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS
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RIGHT VENTRICULAR DYSFUNCTION IN SEPSIS: AN UPDATED NARRATIVE REVIEW.

Mridul Bansal1, Aryan Mehta1, Akshay Machanahalli Balakrishna2

  • 1Section of Cardiovascular Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

Shock (Augusta, Ga.)
|March 21, 2023
PubMed
Summary

Sepsis can cause heart dysfunction, particularly affecting the right ventricle (RV). This review explores RV dysfunction in sepsis, its causes, detection using biomarkers, and management strategies for better patient outcomes.

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Area of Science:

  • Cardiology
  • Critical Care Medicine
  • Pathophysiology

Background:

  • Sepsis is a life-threatening condition impacting multiple organ systems, including the cardiovascular system.
  • Septic cardiomyopathy, characterized by reversible ventricular dysfunction, is a known complication.
  • While left ventricular dysfunction is well-studied, right ventricular (RV) dysfunction in sepsis requires further investigation.

Conclusions:

  • Understanding RV dysfunction in sepsis is critical for improving patient prognosis.
  • Timely diagnosis and targeted management of RV dysfunction are essential.
  • Further research is needed to fully elucidate the role of RV dysfunction in sepsis outcomes.