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Published on: February 14, 2018
Antifungal γ-Pyrone and Isoprenylated Cyclohexanoids from the Fungus Beenakia informis
Yuliet A Rincón1,2, Gastón E Siless1,2, Fernanda D'Jonsiles2
1Facultad de Ciencias Exactas y Naturales, Departamento de Química Orgánica, Universidad de Buenos Aires, C1428EGA, Buenos Aires, Argentina.
Abstract:
Chemical investigation of the extract of the macroscopic fungus Beenakia informis led to the isolation of a previously unreported γ-pyrone and two new isoprenylated cyclohexanoids, together with speciocin N. Their structures were elucidated spectroscopically and the absolute configuration was determined by comparison of the experimental vs. calculated ECD curves. Three of the compounds showed very good to moderate activity against phytopathogenic fungi.
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