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Published on: December 11, 2019
Fully digital self-screening for atrial fibrillation with patch electrocardiogram
Edvard Liljedahl Sandberg1, Sigrun Halvorsen2,3, Trygve Berge4
1Department of Cardiology, Sorlandet Hospital, Postboks 416 Lundsiden, 4604 Arendal, Norway.
Insights
A fully digital self-screening for atrial fibrillation (AF) using a patch ECG demonstrated excellent feasibility in individuals at risk for stroke. This method detected undetected AF in 2.2% of participants, highlighting its potential for early intervention.
Area of Science:
- Cardiology
- Digital Health
- Public Health Screening
Background:
- Atrial fibrillation (AF) is a prevalent arrhythmia linked to significant mortality, morbidity, and healthcare costs.
- Current guidelines advocate for screening individuals at risk for AF, yet optimal methods and organizational structures remain undefined.
- Early detection of AF is crucial for preventing stroke and other complications.
Purpose of the Study:
- To evaluate the feasibility of a novel, fully digital self-screening procedure for AF.
- To determine the prevalence of previously undetected AF in a at-risk population using continuous patch electrocardiogram (ECG) monitoring.
- To assess the usability and effectiveness of a digital self-screening tool for AF detection.
Main Methods:
- A fully digital, continuous self-screening for AF was conducted using a patch ECG device (ECG247 Smart Heart Sensor) in individuals aged 65+ with stroke risk factors in Norway.
- Participants (N=2118) self-reported clinical data and usability online, receiving digital feedback.
- The study tracked completion rates, monitoring duration, and AF detection rates.
Main Results:
- The study enrolled 2118 participants (mean age 70.1 years, 74% women) with a mean CHA2DS2-VASc score of 2.6.
- A high completion rate of 87.3% (1849 participants) was observed for the ECG self-screening test, with a system usability score of 84.5.
- Atrial fibrillation was detected in 41 individuals (2.2%), indicating a number needed to screen of 45 to identify one unrecognized case.
Conclusions:
- The fully digitalized self-screening procedure for AF proved to be highly feasible and effective in detecting undiagnosed cases within a population at risk for stroke.
- The number needed to screen (45) suggests a practical approach for identifying individuals with AF.
- Further randomized controlled trials with long-term follow-up are warranted to ascertain if this self-screening approach can effectively reduce AF-related complications.
Aims:
Atrial fibrillation (AF) is the most common arrhythmia worldwide. The AF is associated with severe mortality, morbidity, and healthcare costs, and guidelines recommend screening people at risk. However, screening methods and organization still need to be clarified. The current study aimed to assess the feasibility of a fully digital self-screening procedure and to assess the prevalence of undetected AF using a continuous patch electrocardiogram (ECG) monitoring system.
Methods And Results:
Individuals ≥65 years old with at least one additional risk factor for stroke from the general population of Norway were invited to a fully digital continuous self-screening for AF using a patch ECG device (ECG247 Smart Heart Sensor). Participants self-reported clinical characteristics and usability online, and all participants received digital feedback of their results. A total of 2118 individuals with a mean CHA2DS2-VASc risk score of 2.6 (0.9) were enrolled in the study [74% women; mean age 70.1 years (4.2)]. Of these, 1849 (87.3%) participants completed the ECG self-screening test, while 215 (10.2%) did not try to start the test and 54 (2.5%) failed to start the test. The system usability score was 84.5. The mean ECG monitoring time was 153 h (87). Atrial fibrillation was detected in 41 (2.2%) individuals.
Conclusion:
This fully digitalized self-screening procedure for AF demonstrated excellent feasibility. The number needed to screen was 45 to detect one unrecognized case of AF in subjects at risk for stroke. Randomized studies with long-term follow-up are needed to assess whether self-screening for AF can reduce the incidence of AF-related complications.
Clinical Trials:
NCT04700865.
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