Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

522
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
522
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

605
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
605
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

4.1K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.1K
Functional Brain Systems: Reticular Formation01:13

Functional Brain Systems: Reticular Formation

2.1K
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
2.1K
Lobes of the Cerebrum01:22

Lobes of the Cerebrum

809
The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements....
809

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An open multi-center MEG-EEG dataset for studying conscious visual perception.

Scientific data·2026
Same author

An open-access multi-site fMRI dataset for investigating conscious visual perception.

Scientific data·2026
Same author

Conductivity Deviations as Virtual Sources in Magnetoencephalography.

Brain topography·2026
Same author

A Digital Anatomical Atlas of the Human Cerebellum at Subfolial Resolution.

Human brain mapping·2026
Same author

Early Maturation of Functional Connectivity within Dorsal Brain Networks.

Brain connectivity·2026
Same author

Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia.

Nature communications·2026

Related Experiment Video

Updated: Aug 6, 2025

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex
09:00

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

Published on: April 15, 2015

12.4K

A role for retro-splenial cortex in the task-related P3 network.

Diptyajit Das1, Marnie E Shaw2, Matti S Hämäläinen3,4,5

  • 1Department of Neurology, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

Biorxiv : the Preprint Server for Biology
|March 22, 2023
PubMed
Summary

The retro-splenial cortex is identified as a primary source of the P3 event-related potential. This finding offers new insights into the neural origins of the P3 response.

Keywords:
EEGMEGP300fMRIinsular cortexsource analysis

More Related Videos

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

18.8K
How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners
09:52

How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners

Published on: May 31, 2018

7.8K

Related Experiment Videos

Last Updated: Aug 6, 2025

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex
09:00

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

Published on: April 15, 2015

12.4K
Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

18.8K
How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners
09:52

How to Find Effects of Stimulus Processing on Event Related Brain Potentials of Close Others when Hyperscanning Partners

Published on: May 31, 2018

7.8K

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience

Background:

  • The P3 event-related potential is a well-known electrophysiological marker linked to task-relevant sensory events.
  • Despite its widespread use, the precise neural generators of the P3 remain a subject of debate.

Approach:

  • This study employed source analysis integrating magneto- and electroencephalography (M/EEG) data.
  • Functional magnetic resonance imaging (fMRI) and simulation studies were also utilized for comprehensive source localization.
  • An auditory oddball paradigm was used to elicit the P3 response.

Key Points:

  • The retro-splenial cortex, within the ventral cingulate gyrus, is identified as the dominant source of the posterior-central P3.
  • The anterior insular cortex contributes minimally to the main P3 component.
  • Other sources in auditory, somatosensory, and anterior midcingulate cortices show distinct temporal activation patterns.

Conclusions:

  • The retro-splenial cortex is a principal generator of the parietal P3 maximum observed in EEG.
  • These findings necessitate a re-evaluation of interpretations in P3-based research.