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"Normal" blood pressure in chimpanzees.

J W Eichberg1, R E Shade

  • 1Department of Virology and Immunology, Southwest Foundation for Biomedical Research, San Antonio, TX.

Journal of Medical Primatology
|January 1, 1987
PubMed
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Blood pressure in chimpanzees increases with age, with no significant sex differences observed. This study provides a tool for identifying hypertension in chimpanzees, suggesting their use in hypertension research.

Area of Science:

  • Veterinary Medicine
  • Primate Research
  • Cardiovascular Physiology

Background:

  • Routine physical examinations are crucial for monitoring animal health.
  • Understanding physiological parameters in non-human primates is vital for their welfare and research applications.
  • Previous research on chimpanzee blood pressure has been limited.

Purpose of the Study:

  • To establish baseline blood pressure ranges in chimpanzees.
  • To investigate potential differences in blood pressure between male and female chimpanzees.
  • To explore the relationship between age and blood pressure in this species.

Main Methods:

  • Collected 140 blood pressure measurements from male and 170 from female chimpanzees over 3 years.
  • Measurements were taken during routine physical examinations under ketamine sedation.

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  • Statistical analysis was performed to evaluate sex and age-related differences.

    • Main Results:

    • No significant differences in blood pressure were found between male and female chimpanzees.
    • Both systolic and diastolic blood pressure showed significant increases with advancing age.
    • Individual variations in blood pressure were noted.

    Conclusions:

    • Age is a significant factor influencing blood pressure in chimpanzees.
    • The collected data can aid in identifying hypertensive chimpanzees.
    • Chimpanzees may serve as a valuable animal model for human hypertension research.