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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Related Experiment Video

Updated: Aug 6, 2025

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

Engineering optical tools for remotely controlled brain stimulation and regeneration.

Artur Filipe Rodrigues^1,2, Catarina Rebelo^1,2,3, Tiago Reis^1,2,3

¹Center for Neurosciences and Cell Biology, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, 3000-517 Coimbra, Portugal. afcdrodrigues@cnc.uc.pt.

Biomaterials Science

|March 22, 2023

Summary

This summary is machine-generated.

Advanced nanomaterials offer precise light-controlled drug delivery and neuromodulation for neurological disorders. This approach aims to improve brain stimulation and regeneration, overcoming limitations of current treatments.

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Area of Science:

Biomedical Engineering
Neuroscience
Materials Science

Background:

Neurological disorders present significant medical and societal challenges, with current treatments often failing to prevent relapse or disease progression.
Existing pharmacological and non-pharmacological interventions lack precise control over neuronal activity and survival.
Current advanced strategies like drug delivery systems and neuromodulation lack spatial and temporal precision.

Purpose of the Study:

To review recent advancements in using light-responsive nanomaterials for neurological disorder treatment.
To discuss the potential of these materials for precise drug delivery and neuromodulation.
To explore applications in brain stimulation and regeneration.

Main Methods:

Review of literature on light-responsive nanomaterials.
Analysis of drug delivery systems and neuromodulation strategies.
Discussion of light stimulation versus other external stimuli (electromagnetic fields, ultrasound).

Main Results:

Light stimulation offers superior single-cell spatial resolution compared to other external stimuli.
Light-responsive nanomaterials enable on-demand drug delivery and neuromodulation.
These technologies show promise for targeted brain stimulation and regeneration.

Conclusions:

Light-responsive nanomaterials represent a promising frontier for treating neurological disorders.
Achieving precise spatial and temporal control is key to overcoming limitations of current therapies.
Future research should focus on harnessing light-responsive nanomaterials for enhanced brain stimulation and regeneration.