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WAVE facilitates polarized E-cadherin transport

Luigy Cordova-Burgos1, Deepti Rao1, Joshua Egwuonwu1

  • 1Department of Pathology and Laboratory Medicine, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854.

Molecular Biology of the Cell
|March 22, 2023
PubMed
Summary

WAVE proteins are crucial for cell polarity by directing cadherin transport to specific cellular locations. This mechanism is essential for proper cell adhesion and development, and its disruption is linked to diseases like cancer.

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