Related Experiment Video
Updated: Jul 12, 2026
Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
Finger Necrosis After Cutaneous Wart Intralesional Injection with Candida albicans Antigen: A Case Report
1The Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, Pennsylvania.
Case:
A 25-year-old man presented 18 hours after Candida albicans antigen injection into a left index finger cutaneous wart by his dermatologist. He experienced a rapid-onset inflammatory response, which was indistinguishable from gangrenous infection. Urgent incision and drainage was performed; however, no purulent collection was noted and no organism isolated. At 1-year follow-up, he made a full recovery.
Conclusion:
Intralesional C. albicans antigen injection in digital cutaneous warts may cause an exaggerated immune response resulting in partial necrosis of the finger pulp. The clinical presentation may be difficult to distinguish from coexisting infection, but in some cases, observation may be an appropriate course of action.
