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Leuconostoc mesenteroides bacteremia in a patient with exposure to unpasteurised raw milk
1Internal Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA simmel@tulane.edu.
Abstract:
Leuconostoc spp are lactic acid-producing bacteria closely related to the Streptococcus family. While usually associated with the fermentation of dairy products and sauerkraut, they are rarely associated with human infections. This is a case report of an immunocompetent patient found to have L. mesenteroides bacteremia associated with raw milk and poor dentition as the likely source of infection, which was treated successfully with daptomycin as this genus is intrinsically resistant to vancomycin.
Insights
Leuconostoc mesenteroides bacteremia is rare in immunocompetent individuals. This case highlights raw milk and poor dentition as potential sources, successfully treated with daptomycin due to vancomycin resistance.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Case Study
Background:
- * *Leuconostoc* species are lactic acid bacteria, typically found in fermented foods.
- * These bacteria are infrequently implicated in human infections, especially in immunocompetent hosts.
Observation:
- * A case report details an immunocompetent patient with *L. mesenteroides* bacteremia.
- * The likely sources identified were consumption of raw milk and poor dental hygiene.
Findings:
- * *Leuconostoc* species exhibit intrinsic resistance to vancomycin.
- * The patient's bacteremia was successfully treated with daptomycin.
Implications:
- * This case expands the understanding of *Leuconostoc* spp. as potential human pathogens.
- * It underscores the importance of considering oral health and dietary sources in rare bacterial infections.
- * Daptomycin is a viable treatment option for *Leuconostoc* bacteremia, particularly when vancomycin is ineffective.
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