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Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction
Xin Qian1,2, Xing Tao1,2, Yangyang Gong1
1Department of Urology, Suining Central Hospital, Suining, 629000, Sichuan Province, China.
Basic and Clinical Andrology
|March 23, 2023
Summary
Elevated homocysteine levels inhibit penile erection, negatively correlating with rigidity and tumescence parameters measured by the RigiScan test. This study explores the link between homocysteine and erectile function.
Area of Science:
- Urology
- Andrology
- Biochemistry
Background:
- Elevated homocysteine is linked to erectile dysfunction.
- The specific impact of homocysteine on penile tip and base erection requires further investigation.
Purpose of the Study:
- To investigate the correlation between homocysteine levels and penile erection parameters.
- To determine if homocysteine affects erection rigidity and tumescence at the penile base and tip.
Main Methods:
- Utilized the RigiScan device to measure penile rigidity and tumescence.
- Analyzed the correlation between serum homocysteine levels and RigiScan parameters.
Main Results:
- Homocysteine levels showed a negative correlation with average event rigidity of the penile base (r=-0.2225, p=0.0142).
- A negative correlation was observed between homocysteine levels and average maximum rigidity of the penile base (r=-0.2164, p=0.0171).
- Homocysteine levels were negatively correlated with changes in tumescence at the penile tip (∆ Tumescence, r=-0.1866, p=0.0404) and base (r=-0.2257, p=0.0128).
Conclusions:
- Homocysteine inhibits penile erection.
- Homocysteine levels are negatively associated with key parameters assessed by the RigiScan test, indicating its detrimental effect on erectile function.
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