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Updated: Aug 6, 2025

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Primary vulvar melanoma in an adolescent patient
Kathy P Li1, Etsubdenk M Ajebo1, Davis Diamond1
1Department of Dermatology, Medical College of Georgia at Augusta University, Augusta, Georgia, USA.
Abstract:
Herein we describe the case of a Black adolescent who was found to have widely metastatic melanoma originating from a primary vulvar lesion. The lesion presented as a pink, vegetative nodule of the clitoral hood which grew in size over several years and was confirmed to be melanoma on shave biopsy. This patient's amelanotic presentation in conjunction with the rare incidence of vulvar melanoma contributed to the delay in diagnosis. This case exemplifies the challenge of early recognition of potentially malignant vulvar lesions for primary care providers in adolescents.
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