Related Experiment Video
Updated: Aug 6, 2025

04:57
Author Spotlight: Advancing Spectral Characterization of Physiological and Malperfused Tissues
Published on: July 5, 2024
509
Case report: Multi-site perfusion strategy for type A acute aortic dissection complicated with cerebral malperfusion
Santiago Besa1, Fiorenza Castelli2, Luis Garrido-Olivares1
1Division of Surgery, Department of Cardiovascular Surgery, Pontificia Universidad Católica de Chile, Santiago, Chile.
Frontiers in Cardiovascular Medicine
|March 23, 2023
Summary
Acute type A aortic dissection with cerebral malperfusion is dangerous. A multi-site perfusion strategy and Hybrid Frozen Elephant Trunk graft successfully restored cerebral circulation, improving outcomes in a complex case.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Vascular Surgery
Background:
- Acute type A aortic dissection (aTAAD) poses significant risks, especially when presenting with cerebral malperfusion.
- Cerebral malperfusion in aTAAD often involves complex vascular issues, complicating surgical candidacy and treatment.
- High morbidity and mortality rates are associated with aTAAD complicated by neurological deficits.
Observation:
- A 48-year-old male presented with paraplegia and decreased consciousness due to acute type A aortic dissection.
- Computed Tomography revealed complete occlusion of both common carotid arteries in the affected patient.
- The patient's complex presentation included severe neurological compromise and extensive aortic pathology.
Findings:
- Successful treatment was achieved using a multi-site perfusion strategy combined with a Hybrid Frozen Elephant Trunk graft.
- This approach rapidly restored cerebral blood flow, mitigating ischemic brain injury.
- The surgical intervention addressed both the aortic dissection and the critical cerebral vessel occlusion.
Implications:
- Aggressive aortic arch and neck vessel reconstruction, supported by multi-site perfusion, can be a viable strategy for selected aTAAD patients.
- This case highlights the potential for improved mortality and neurological outcomes in complex aTAAD cases.
- The presented technique offers a promising option for managing life-threatening cerebral malperfusion in acute aortic dissections.
Keywords:
Frozen Elephant Trunk (FET)aortic arch surgeryaortic dissectioncase reportcerebral malperfusion
