[Ischemic heart disease and the biological age of men over 40]

Area of Science:

• Cardiovascular physiology
• Gerontology
• Endocrinology

Background:

• Assessing biological age is crucial for understanding health and disease risk in aging populations.
• Cardiovascular and respiratory functions are key indicators of physiological aging.
• Hormonal status plays a significant role in cardiovascular health and aging processes.

Purpose of the Study:

• To estimate biological age in 40- to 64-year-old males.
• To investigate the relationship between biological age, cardiovascular/respiratory function, and hormonal status.
• To identify factors contributing to cardiovascular pathology.

Main Methods:

• Examined a population of 40- to 64-year-old males, including normal subjects and coronary patients.
• Utilized cardiovascular and respiratory functional parameters for biological age estimation.
• Employed multiple regression analysis and dynamometry in relation to hormonal status.

Main Results:

• Biological age estimation was based on cardiovascular and respiratory functional parameters.
• Hormonal status was analyzed in relation to biological age and cardiovascular health.
• Findings suggest hormonal status is a contributing factor to cardiovascular pathology.

Conclusions:

• Biological age can be estimated using cardiovascular and respiratory functional parameters in middle-aged men.
• Hormonal status is a significant factor influencing biological age and cardiovascular disease risk.
• These findings contribute to understanding the pathophysiology of cardiovascular diseases.