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Updated: Aug 6, 2025

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Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
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Aptamer-modified Zr-MOFs to construct nanocatalysts with engineered specificity toward paraoxon
Tingwei Cao1, Jiaxing Zhang1, Wei Qi1,2,3
1School of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, Tianjin University, Tianjin 300350, P. R. China.
Abstract:
Aptamer-modified Zr-MOFs (UiO-66-APT) were constructed as nanocatalysts for achieving specific hydrolysis of paraoxon. The conjunction mode of the aptamer on the Zr-MOFs affected the binding of the substrates with the catalytic sites, thus leading to different catalytic activities. This study provides a solution for achieving specific catalysis of nanocatalysts, just like that in natural enzymes.

