Peroxisomes and Viruses: Overview on Current Knowledge and Experimental Approaches.
Vanessa Ferreira1, Ana Rita Ferreira1, Daniela Ribeiro2
1Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal.
Methods in Molecular Biology (Clifton, N.J.)
|March 23, 2023
Summary
Viruses interact with peroxisomes, impacting cellular antiviral defenses and viral spread. Further research into these viral-peroxisome interactions could reveal new antiviral therapy targets.
Area of Science:
- Cell Biology
- Virology
- Biochemistry
Background:
- Growing interest in peroxisome roles in viral infections.
- Viruses manipulate peroxisome pathways to evade immunity or enhance replication.
- Mechanistic details of virus-peroxisome interplay remain largely unknown.
Conclusions:
- Detailed spatiotemporal studies are essential for uncovering novel peroxisome functions in viral infections.
- Peroxisome-virus interactions represent a promising area for developing new antiviral strategies.
Keywords:
Antiviral responseInnate immunityMAVSPeroxisome biogenesisPeroxisome metabolismPeroxisomesViral infectionVirusMore Related Videos
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