Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

45.0K
Overview
45.0K
PPE Use in Healthcare Settings I: Donning01:22

PPE Use in Healthcare Settings I: Donning

1.1K
Donning PPE must be completed before contact with the patient. This process protects from infectious agents. The sequence and action included in each donning are critical, and the steps must be systematic to avoid exposure to pathogens. The institutional policy also needs to be followed while donning PPE. The pre-donning preparations are gathering equipment, inspecting the PPE equipment for tears, holes, or damage, removing jewelry, removing any garments below the elbows, and tying the hair...
1.1K
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.3K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.3K
PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

978
The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
978
Development of Immunocompetence01:22

Development of Immunocompetence

392
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
392
Nursing Implementation01:15

Nursing Implementation

5.1K
Implementation is the execution of the nursing care plan developed during the planning phase.
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of a Standardized Approach to Healthcare Worker Hazardous Medication Surveillance: Lessons learned and future enhancements.

Journal of occupational and environmental medicine·2026
Same author

Optimizing tuberculosis post-exposure follow-up among healthcare personnel using a risk-based approach.

Infection control and hospital epidemiology·2026
Same author

How Health Care Providers Are Contributing to the Iatrogenic Disability Crisis in the United States.

Mayo Clinic proceedings·2025
Same author

Adapting the World Health Organization 5 Well-Being Index for Emergency Activation and Response Planning in a US Health Care Setting.

Mayo Clinic proceedings. Innovations, quality & outcomes·2025
Same author

Adding employment status in the medical record demonstrates its importance as a social determinant of health.

JAMIA open·2025
Same author

Laboratory Animal Allergy.

Journal of occupational and environmental medicine·2025

Related Experiment Video

Updated: Aug 6, 2025

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

10.7K

Early Experience With an Occupational JYNNEOS ( Orthopoxvirus ) Vaccination Program.

Melanie D Swift1, Mary C McDermott, Caitlin M Hainy

  • 1From the Occupational Health Services, Mayo Clinic, Rochester, Minnesota (M.D.S., M.C.M., C.M.H., J.A.A., J.J.M., L.E.B.); Division of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinic, Rochester, Minnesota (M.D.S., L.E.B.); and Pharmacy, Mayo Clinic, Rochester, Minnesota (C.J.A.).

Journal of Occupational and Environmental Medicine
|March 23, 2023
PubMed
Summary

Laboratory workers accepted JYNNEOS vaccine for orthopoxvirus exposure, citing occupational risk. Careful planning is crucial for occupational health programs managing non-commercial vaccines and CDC requirements.

More Related Videos

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells
10:03

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells

Published on: August 1, 2013

17.0K
Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

11.5K

Related Experiment Videos

Last Updated: Aug 6, 2025

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

10.7K
Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells
10:03

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells

Published on: August 1, 2013

17.0K
Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

11.5K

Area of Science:

  • Occupational Health
  • Vaccinology
  • Infectious Disease Control

Background:

  • Laboratory workers face potential exposure to orthopoxviruses, including mpox.
  • JYNNEOS is a vaccine recommended for individuals at risk of orthopoxvirus infection.
  • Implementing vaccination programs in high-risk laboratory settings presents unique challenges.

Purpose of the Study:

  • To identify lessons learned from implementing JYNNEOS vaccination for laboratory workers.
  • To document the process of vaccine procurement and administration under an occupational health program.
  • To understand reasons for vaccine acceptance or declination and associated adverse effects.

Main Methods:

  • A planned occupational health program offered JYNNEOS vaccination to at-risk laboratory workers.
  • Vaccine was procured through the Centers for Disease Control and Prevention (CDC) Drug Service.
  • Surveys were used to collect data on vaccine acceptance, reasons for decisions, and adverse effects.

Main Results:

  • The majority of laboratory workers accepted JYNNEOS vaccination.
  • Occupational risk was the primary reason cited for vaccine acceptance.
  • Most vaccine recipients experienced mild, localized adverse effects.
  • The administrative procedures of the CDC Drug Service were documented.

Conclusions:

  • Effective occupational health programs require meticulous planning and coordination for laboratory workers handling novel biological agents.
  • Facilitating access to non-commercially available vaccines is a key component of such programs.
  • Anticipating and mitigating barriers to vaccination, alongside compliance with specific regulatory requirements (e.g., CDC), is essential.