Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Luteal phase insufficiency: clinical aspects.

J Balasch1

  • 1Department of Obstetrics and Gynecology, Faculty of Medicine, Hospital Clínico y Provincial, Barcelona, Spain.

Journal of Steroid Biochemistry
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postnatal persistence of fetal cardiovascular remodelling associated with assisted reproductive technologies: a cohort study.

BJOG : an international journal of obstetrics and gynaecology·2018
Same author

Fetal cardiac remodeling in twin pregnancy conceived by assisted reproductive technology.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2017
Same author

Total circulating microparticle levels are increased in patients with deep infiltrating endometriosis.

Human reproduction (Oxford, England)·2016
Same author

Risk Factors for Changes of Fibrinolysis During Benign Adnexal Laparoscopic Surgery.

Journal of minimally invasive gynecology·2016
Same author

Differential effect of assisted reproductive technology and small-for-gestational age on fetal cardiac remodeling.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2016
Same author

Adverse urinary effects of allopurinol in dogs with leishmaniasis.

The Journal of small animal practice·2016
Same journal

Preferential nuclear binding of estrogen in the formalin-fixed rat uterus.

Journal of steroid biochemistry·1990
Same journal

Properties of estrogen and hydroxysteroid sulphotransferases in human mammary cancer.

Journal of steroid biochemistry·1990
Same journal

Alterations in the binding characteristics of glucocorticoid receptors from obese Zucker rats.

Journal of steroid biochemistry·1990
Same journal

In vitro inhibition by ketoconazole of human testicular steroid oxidoreductases.

Journal of steroid biochemistry·1990
Same journal

Testing for fluoxymesterone (Halotestin) administration to man: identification of urinary metabolites by gas chromatography-mass spectrometry.

Journal of steroid biochemistry·1990
Same journal

The state transitions of normal and mutant androgen-receptor complexes in human genital skin fibroblasts.

Journal of steroid biochemistry·1990
See all related articles

Diagnosing luteal phase insufficiency (LPI) is complex, as midluteal progesterone levels lack predictive value for endometrial transformation. Accurate LPI diagnosis requires multiple endometrial biopsies, and follicular phase factors are key to understanding its etiology and effective treatment.

Area of Science:

  • Reproductive Endocrinology
  • Gynecology
  • Infertility Research

Background:

  • Luteal phase insufficiency (LPI) is a debated condition affecting female fertility.
  • Current diagnostic methods for LPI face significant challenges and controversies.
  • Understanding LPI's etiology and effective treatments remains crucial for reproductive health.

Purpose of the Study:

  • To critically analyze controversial clinical aspects of luteal phase insufficiency (LPI).
  • To evaluate the diagnostic utility of midluteal progesterone and endometrial biopsies.
  • To explore the role of follicular phase determinants and therapeutic strategies for LPI.

Main Methods:

  • Analysis of clinical data focusing on luteal phase insufficiency.
  • Evaluation of midluteal plasma progesterone assays for diagnostic accuracy.

Related Experiment Videos

  • Review of endometrial biopsy protocols for LPI diagnosis.
  • Examination of etiological factors, particularly from the follicular phase.
  • Discussion of therapeutic interventions for LPI and their impact on fertility.

    • Main Results:

    • Midluteal plasma progesterone levels show limited predictive value for endometrial transformation.
    • Accurate diagnosis of LPI may necessitate a minimum of two to three endometrial biopsies.
    • Follicular phase characteristics are significant determinants of LPI.
    • Various therapeutic approaches for LPI are discussed regarding their effectiveness.

    Conclusions:

    • The diagnosis of luteal phase insufficiency is complex and requires careful consideration of multiple factors.
    • Current diagnostic markers like progesterone assays have limitations.
    • Emphasis on follicular phase evaluation and multi-biopsy assessment is crucial for LPI diagnosis.
    • Therapeutic strategies should be tailored, considering their impact on fertility outcomes.