Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intrapulpal nerve stimulation in the rat.

N Myslinski1, B Matthews

  • 1Department of Physiology, Medical School, Bristol, U.K.

Journal of Neuroscience Methods
|November 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Air quality assessment of a mass deployment of microgrids.

The Science of the total environment·2024
Same author

Thalamocortical Projections Are Significantly Impaired in the R6/2 Mouse Model of Huntington's Disease.

eNeuro·2022
Same author

Management of complex ventral hernias: results of an international survey.

BJS open·2021
Same author

Bioactive compounds sourced from Terminalia spp. in bacterial malodour prevention: an effective alternative to chemical additives.

International journal of cosmetic science·2019
Same author

Inequality in access to hearing care for older adults in residential homes.

Journal of public health (Oxford, England)·2019
Same author

Humanitarianism in surgery.

Hernia : the journal of hernias and abdominal wall surgery·2017
Same journal

Pupil-DLC: an open-source deep learning pipeline for scalable, marker-less tracking of pupil dynamics across conscious and unconscious states.

Journal of neuroscience methods·2026
Same journal

Time as the language of Behavior: events, sequences, patterns and meanings.

Journal of neuroscience methods·2026
Same journal

Detection of cochlear microphonic for differential diagnosis between auditory neuropathy mice and noise-induced sensorineural hearing loss mice.

Journal of neuroscience methods·2026
Same journal

Assessment metrics for pain control in rats: A methodological commentary.

Journal of neuroscience methods·2026
Same journal

Infant EEG preprocessing pipelines: A capability framework and current gaps in practice.

Journal of neuroscience methods·2026
Same journal

Methods for measuring neural activity during voluntary wheel running.

Journal of neuroscience methods·2026
See all related articles

Researchers developed a new electrical stimulation method to selectively target dental pulp nerves in rats. This technique helps verify stimulation of pulpal afferents, crucial for pain research.

Area of Science:

  • Neuroscience
  • Pain Research
  • Dental Research

Background:

  • Electrical stimulation of rat incisor pulp is common for pain mechanism studies.
  • Existing methods often stimulate non-pulpal nerves alongside pulpal ones.
  • Selective stimulation of pulpal nerves is needed for accurate pain research.

Purpose of the Study:

  • To develop and verify a procedure for selective electrical stimulation of rat incisor pulpal nerves.
  • To differentiate between pulpal and extrapulpal nerve activation during electrical stimulation.
  • To provide a reliable method for nociceptive researchers to confirm pulpal afferent stimulation.

Main Methods:

  • Electrodes were placed in labial cavities of rat lower incisors.
  • Constant current stimuli were applied between electrodes.

Related Experiment Videos

  • Electromyography (EMG) monitored digastric muscle reflex activation.
  • Pulpal nerve stimulation was verified by sectioning the tooth pulp.

    • Main Results:

    • Two response components were observed: a long latency potential (LLP) and a short latency potential (SLP).
    • The LLP (37 ms latency) was abolished by pulp sectioning, indicating pulpal origin.
    • The SLP (12 ms latency) persisted after pulp sectioning, suggesting extrapulpal origin.
    • The threshold for LLP was significantly lower (89 microA) than for SLP (650 microA).

    Conclusions:

    • The developed method selectively stimulates pulpal nerves via LLP.
    • The SLP likely results from extrapulpal nerve excitation.
    • This technique offers a reliable way to ensure pulpal afferent stimulation in nociceptive research.