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Related Experiment Videos

High efficiency plasmapheresis using rotating membrane device.

G Beaudoin1, M Y Jaffrin

  • 1Department of Biological Engineering, Université de Technologie de Compiègne BP 233, France.

Life Support Systems : the Journal of the European Society for Artificial Organs
|July 1, 1987
PubMed
Summary
This summary is machine-generated.

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This study investigates how blood pressure and rotation speed affect a rotating membrane plasmapheresis device. Optimal performance is linked to high shear rates, cell centrifugation, and secondary flows.

Area of Science:

  • Biomedical Engineering
  • Renal Replacement Therapies

Background:

  • Plasmapheresis is a medical procedure to remove plasma from blood.
  • Rotating membrane devices offer a novel approach to plasmapheresis.

Purpose of the Study:

  • To experimentally investigate the impact of inlet blood pressure and rotation speed on plasmapheresis device performance.
  • To identify key factors contributing to the device's efficacy.

Main Methods:

  • Experimental setup to control and measure inlet blood pressure and rotation speed.
  • Performance evaluation of a commercial rotating membrane plasmapheresis device.

Main Results:

  • Inlet blood pressure and rotation speed significantly influence device performance.

Related Experiment Videos

  • High shear rate, centrifugation of red blood cells and platelets, and secondary flows contribute to effective plasmapheresis.

    • Conclusions:

    • The performance of the Hemascience rotating membrane plasmapheresis device is optimized by specific operational parameters.
    • Understanding these parameters is crucial for maximizing therapeutic outcomes in plasmapheresis procedures.