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Malic enzyme response to triiodothyronine in the brain of neonatal rats

U R Thakare1, U Vijayan, L Sushila

  • 1Radiation Medicine Centre, Tata Memorial Centre, Parel, Bombay, India.

Life Sciences
|December 28, 1987
PubMed

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...